What truly motivates us to act and accomplish our goals? Motivation is the fundamental psychological construct that drives most human behavior, shaping decision-making and goal-directed action...
Background: Pakistan has a high TB burden, but the diagnosis, particularly in children and adolescents, is often delayed. We conducted a study to understand the barriers and facilitators to th...
Opioid use disorder (OUD) is a global health crisis, affecting over 16 million people and contributing to approximately 120,000 deaths annually. Driven by the prolonged use of opioids like...
Drawing on data from the QIAGEN Knowledge Base (QKB) and GEO public datasets using a machine learning algorithm (Ingenuity Pathway Analysis [IPA]), a network meta-analysis on the molecular...
Expansion of white adipose tissue (WAT) via recruitment of adipocytes (hyperplasia) is metabolically healthy, whereas that through the enlargement of pre-existing adipocytes (hypertrophy) lead...
Butyrate, a bacterial derived short chain fatty acid is implicated in gastrointestinal, immunological and host cell metabolic functions. The present study was undertaken to evaluate the role...
Background: Muscle wasting (MW) accompanied by systemic inflammation contributes to poor prognosis in critical illnesses, including burn injury (BI). Studies on aging have identified sarcopeni...
Introduction: Mitophagy, the autophagic degradation of mitochondria, is a conserved quality control system critical for cellular health. Dysregulation of mitophagy contributes to various huma...
Purpose: Fuchs Endothelial Corneal Dystrophy (FECD) is an oxidative stress disorder leading to accelerated loss of corneal endothelial cells (CEnCs) and exhibits greater accumulation of DNA...
First-generation Cephalosporin antibiotics like Cephalexin are strong -lactams that are often utilised in veterinary medicine throughout many nations. Cephalexin is relatively resistant to the...