Applied – ASSET https://assetonline.org Sat, 27 Dec 2025 18:03:04 +0000 en-US hourly 1 https://wordpress.org/?v=6.9 https://assetonline.org/wp-content/uploads/2021/03/cropped-icon-32x32.png Applied – ASSET https://assetonline.org 32 32 The Relationship Between Barometric Pressure Changes and Weather-Related Headaches https://assetonline.org/the-relationship-between-barometric-pressure-changes-and-weather-related-headaches-2/ Sat, 27 Dec 2025 18:03:04 +0000 https://assetonline.org/?p=5976

Weather-related headaches have been reported more frequently during rainy season, particularly in fall and winter. Previous researcher suggested that changes in barometric pressure can cause headaches, dizziness, or join pain, this condition is known as meteropathy. Approximately 30% of the global population or 2.4 billion people experience weather-related physical symptoms. Although meteoropathy is not life-threatening, it can significantly affect daily functioning quality of life. Barometric pressure is the pressure caused by the weight of the air. Change in barometric pressure can affect the middle ear, an air-filled cavity connected to the back of the nose through Eustachian tube. Under normal conditions, this tube equalizes internal and external air pressure. However, when barometric pressure changes rapidly, the eustachian tube may not open properly. This can create imbalances of pressure, placing stress on the eardrum and disturbance in inner-ear fluids balance. These changes can interfere with signals sent to the brain, potentially causing headaches, dizziness, or even fainting. To investigate the relationship between barometric pressure and headaches, and weather-related headaches, long-term barometric data were analyzed using NASA Earth observation datasets. The data recorded on September 2025 reveal a significant drop in barometric pressure between September 26 and 27, with a decrease of approximately 9 hPa within one day. Previous research indicates that pressure drops as small as 5hPa can increase the likelihood of meteoropathy symptoms, suggesting that this rapid decline represented a high-risk condition for weather-related headaches. Further analysis involved comparing cumulative distribution function graphs of Seattle, Boston and Miami. Each line on the graph represents a season (spring, summer, fall, or winter), and the vertical line at x = -5 hPa marks the threshold at which weather-related symptoms are more likely to occur. In Seattle, the probability of experiencing a pressure drop of 5 hPa is only about 4% in summer but increases dramatically to about 22% in winter. Boston shows a similar but slightly higher pattern, while Miami remains below 5% across all seasons, indicating a lower likelihood of weather-related symptoms. The difference is likely due to Miami more stable climate, whereas Seattle and Boston are more frequently affected by strong storm system. In conclusion, the data strongly suggested a clear relationship between barometric pressure change and weather-related headaches. Large barometric pressure changes occur much more often during fall and winters, especially in cities like Seattle and Boston. These frequent pressure changes explain why weather-related headaches are more common during colder seasons. Understanding these patterns can help explain how weather is related to human health and why some regions experience more symptoms than others.

Authors List :
Konomi Karube
Presenting Author :
Konomi Karube
Affiliations :
Lake Washington High School
Email :
ko.karube@outlook.com
Key Words (5 Words Maximum) :
Headache, Barometric Pressure, Weather, Meteropathy
]]> The Relationship Between Barometric Pressure Changes and Weather-Related Headaches https://assetonline.org/the-relationship-between-barometric-pressure-changes-and-weather-related-headaches/ Thu, 25 Dec 2025 23:07:19 +0000 https://assetonline.org/?p=5978

Background: Weather-related headaches have been reported more frequently during rainy season, particularly in fall and winter. Previous researcher suggested that changes in barometric pressure can cause headaches, dizziness, or join pain, this condition is known as meteropathy. Approximately 30% of the global population or 2.4 billion people experience weather-related physical symptoms. Although meteoropathy is not life-threatening, it can significantly affect daily functioning quality of life.
Barometric pressure is the pressure caused by the weight of the air. Change in barometric pressure can affect the middle ear, an air-filled cavity connected to the back of the nose through Eustachian tube. Under normal conditions, this tube equalizes internal and external air pressure. However, when barometric pressure changes rapidly, the eustachian tube may not open properly. This can create imbalances of pressure, placing stress on the eardrum and disturbance in inner-ear fluids balance. These changes can interfere with signals sent to the brain, potentially causing headaches, dizziness, or even fainting.
To investigate the relationship between barometric pressure and headaches, and weather-related headaches, long-term barometric data were analyzed using NASA Earth observation datasets.
Results: The data recorded on September 2025 reveal a significant drop in barometric pressure between September 26 and 27, with a decrease of approximately 9 hPa within one day. Previous research indicates that pressure drops as small as 5hPa can increase the likelihood of meteoropathy symptoms, suggesting that this rapid decline represented a high-risk condition for weather-related headaches.
Further analysis involved comparing cumulative distribution function graphs of Seattle, Boston and Miami. Each line on the graph represents a season (spring, summer, fall, or winter), and the vertical line at x = -5 hPa marks the threshold at which weather-related symptoms are more likely to occur. In Seattle, the probability of experiencing a pressure drop of 5 hPa is only about 4% in summer but increases dramatically to about 22% in winter. Boston shows a similar but slightly higher pattern, while Miami remains below 5% across all seasons, indicating a lower likelihood of weather-related symptoms. The difference is likely due to Miami more stable climate, whereas Seattle and Boston are more frequently affected by strong storm system. In conclusion, the data strongly suggested a clear relationship between barometric pressure change and weather-related headaches. Large barometric pressure changes occur much more often during fall and winters, especially in cities like Seattle and Boston. These frequent pressure changes explain why weather-related headaches are more common during colder seasons. Understanding these patterns can help explain how weather is related to human health and why some regions experience more symptoms than others.

Authors List :
Konomi Karube
Presenting Author :
Konomi Karube
Affiliations :
Lake Washington High School
Email :
ko.karube@outlook.com
Key Words (5 Words Maximum) :
Headache, Barometric Pressure, Weather, Meteropathy
]]> Integration of Bioinformatics and Statistical Tools in Biomedical Research https://assetonline.org/integration-of-bioinformatics-and-statistical-tools-in-biomedical-research/ Thu, 25 Dec 2025 20:00:19 +0000 https://assetonline.org/?p=5923

The continuous and rapid growth of high-throughput biological data has made the integration of bioinformatics and statistical tools essential in biomedical research. It is deemed essential because of its applicability across several domains like genetics, microbiology, and drug screening for computational and statistical methodologies for data analysis, sequence alignment, and predictive modeling. Bioinformatics tools such as sequence alignment algorithms, genomic databases, and molecular modeling platforms make handling efficient and interpretation of large-scale biological datasets is sped up while maintaining accuracy during handling. Data validation, hypothesis testing, pattern recognition, and model evaluation is executed flawlessly. In genetics it is often utilized in gene identification and annotation, variant and mutation analysis, Genome-wide association studies (GWAS), and similarly in microbiology it is used in microbial genome sequencing, species identification and classification. In drug screening bioinformatics handles and interprets the biological data and statistical tools to analyze the large data and find meaningful patterns so the researchers can identify the potential drug targets, predict how the drug might interact with proteins and analyze the screening results. With determination researchers are quickly adapting to advanced machine learning and AI integration for personalized medicine and precision healthcare while setting up the foundation for real-time genomic and clinical data analysis and automated drug discovery pipelines. In conclusion, integration of bioinformatics and statistical tools is indispensable in modern biomedical research which enables comprehensive analysis across genetics, microbiology, and drug discovery, driving innovation in diagnostics, therapeutics, and personalized medicine.

Authors List :
Adiva Baig, Humera Quadriya, Fehmida Begum, Shagufta Tarannum, Majid Mohiuddin
Presenting Author :
Adiva Baig
Affiliations :
Anwarul Uloom College
Email :
adivabaig@gmail.com
Key Words (5 Words Maximum) :
Artificial intelligence, Bioinformatics, Genome-wide association studies (GWAS), Machine learning, Statistical analysis
]]> Thyroid Disorders and Their Impact on Human Health https://assetonline.org/thyroid-disorders-and-their-impact-on-human-health/ Thu, 25 Dec 2025 19:19:21 +0000 https://assetonline.org/?p=5901 Thyroid hormones play a crucial role in regulating metabolic processes, growth, and development, and maintaining cardiovascular, physical, and mental health. Disruption of thyroid gland activity can lead to hypothyroidism or hyperthyroidism, both of which may result in serious illness if undiagnosed or inadequately treated. Hypothyroidism is most commonly managed through replacement therapy with levothyroxine (LEVO), a synthetic form of thyroxine, while hyperthyroidism is treated using anti-thyroid drugs, radioactive iodine, or thyroidectomy. These therapies are typically administered via oral, intravenous, or rectal routes. Despite long-standing clinical use, conventional treatment approaches are associated with several challenges, including poor patient compliance, variable gastrointestinal absorption, and significant interactions with food and other medications, often leading to sub-optimal dosing and adverse clinical outcomes. The thyroid gland, located in the anterior neck, synthesizes and secretes triiodothyronine (T3) and thyroxine (T4), with T3 being the biologically active form. Although both hormones are produced by the thyroid, approximately 80% of circulating T3 is generated through peripheral conversion of T4. Thyroid hormone secretion is tightly regulated by the hypothalamic–pituitary–thyroid axis via a negative feedback mechanism involving thyrotropin-releasing hormone and thyroid-stimulating hormone. Hypothyroidism is characterised by insufficient thyroid hormone production and affects approximately 5% of the global population, with a similar proportion remaining undiagnosed. Primary hypothyroidism accounts for the majority of cases and is commonly caused by iodine deficiency or autoimmune conditions such as Hashimoto’s thyroiditis. Given the limitations of current therapies, there remains a clear need for novel drug delivery approaches to improve bioavailability, dosing accuracy, and patient compliance. This review highlights conventional treatment strategies and explores emerging drug delivery systems aimed at improving therapeutic outcomes in thyroid disorders.

Authors List :
Mohammed Saif Ali, Humera Quadriya, Shagufta Tarannum, Fehmida Begum, Majid Mohiuddin
Presenting Author :
Mohammed Saif Ali
Affiliations :
Anwarul Uloom College
Email :
hafizsaif940@gmail.com
Key Words (5 Words Maximum) :
Hashimoto’s thyroiditis, Levothyroxine, Nanoformulations, Thyroid gland, Thyrotropin
]]> Beneficial Microbial Blueprint For Sustainable Future https://assetonline.org/beneficial-microbial-blueprint-for-sustainable-future/ Sun, 21 Dec 2025 10:19:19 +0000 https://assetonline.org/?p=5835

The growing challenges of climate change, environmental deterioration, and resource scarcity need a shift towards biological solutions. Microorganisms play a key role in preserving ecological balance and fostering sustainable growth through their various metabolic capacities. The concept of a beneficial microbial blueprint emphasizes the strategic identification, optimization, and deployment of functional microorganisms and their bioactive metabolites to address global concerns in agriculture, healthcare, industry, and the environment. Beneficial bacteria help to promote sustainable agriculture by cycling nutrients, fixing nitrogen, solubilizing phosphate, and controlling plant diseases, lowering the need for chemical fertilizers and pesticides. In healthcare and biotechnology, microbial secondary metabolites such as biosurfactants, bioactive pigments, enzymes and antibiotics provide sustainable alternatives with antibacterial, anticancer, and immunomodulatory therapeutic properties. Algae-derived substances, such as phycocyanin and polysaccharides from microalgae like Chlorella and Spirulina, have antiviral, neuroprotective and anti-inflammatory properties that can be used in the formulation of novel drugs. Furthermore, microbes are essential for ecological sustainability as they enable waste decomposition, bioremediation, and bioenergy production. Oleaginous algae such as Chlorella vulgaris efficiently convert biomass into precursors of bioethanol and biodiesel through fermentation pathways and lipid accumulation. Microbial fuel cells (MFCs) combine bioremediation with the generation of renewable energy by using electroactive bacteria that generate electricity directly from organic waste. Development in synthetic biology, omics technology including tools of artificial technology (AI) have significantly improved our capacity to harness microbial potential with increased specificity and efficiency. This talk will emphasize the use of beneficial bacteria as a sustainable blueprint for future innovations, boosting green technology and enhancing economic viability. Ultimately, orchestrating microorganisms to microbiomes will give a practical, effective, and sustainable strategy to accomplish the Sustainable Development Goals (SDGs) promoting resilience and guiding human development towards a harmonious coexistence on the planet earth.

Authors List :
Professor Hameeda Bee
Presenting Author :
Hameeda Bee
Affiliations :
Department of Microbiology, UCS, Osmania University
Email :
drhami2009@gmail.com
Key Words (5 Words Maximum) :
Microbes, Blue print, Health care, Agriculture, Environment, Sustainable
]]> Patient-Centric Pharmacovigilance: Development of a Mobile Application for Direct Adverse Drug Reaction Reporting. https://assetonline.org/patient-centric-pharmacovigilance-development-of-a-mobile-application-for-direct-adverse-drug-reaction-reporting/ Sat, 20 Dec 2025 19:00:59 +0000 https://assetonline.org/?p=5831

The increasing prevalence of adverse drug reactions (ADRs) poses a significant threat to public health, while underreporting remains a major limitation of existing pharmacovigilance systems. This paper presents the development of a mobile application, designed to facilitate direct, timely, and structured reporting of ADRs by patients and healthcare professionals.
The application features a user-friendly interface, standardizes ADR reporting forms, and secures data storage to ensure data integrity and confidentiality.
The application aims to improve accessibility, reduces reporting barriers, and enhances patient participation in pharmacovigilance. By empowering patients to report ADRs, we seek to improve drug safety and healthcare outcomes.
The ADR Reporter app demonstrates potential in bridging gaps in existing pharmacovigilance systems, promoting a scalable and patient-centric approach to medication safety, with future potential for integration into national ADR monitoring frameworks.

Authors List :
Mohammad Roohan, Aqsa Athar, Syed Ziaur Rahman
Presenting Author :
Mohammad Roohan, Aqsa Athar
Affiliations :
Department of Pharmacology, JNMC, AMU, Aligarh, India
Email :
m.roohan2010@gmail.com
Key Words (5 Words Maximum) :
ADR, Pharmacovigilance, Reporting
]]> Astrack: A Comprehensive App for Managing Asthma https://assetonline.org/astrack-a-comprehensive-app-for-managing-asthma/ Wed, 11 Dec 2024 01:22:29 +0000 https://assetonline.org/?p=5641 Asthma is a chronic respiratory condition that causes inflammation in the lung airways, known as the bronchial tubes. Asthma causes the bronchial tubes to tighten, and air is unable to reach the lungs, making it difficult to breathe. This condition affects all age groups, but young children and older adults are particularly vulnerable. Asthma is the leading cause of children’s absenteeism from school. Without proper treatment, asthma can worsen and lead to permanent lung damage. Although there is no cure to asthma, there are treatments such as inhalers and oral medications that help manage asthma by expanding the bronchial tubes. However, the risk factors of asthma are commonly overlooked. Studies have proven direct correlations of certain risk factors to asthma, such as obesity and allergies. By monitoring these risk factors and treating them accordingly, we can mitigate the effects of asthma attacks. Therefore, Astrack is introduced as a comprehensive app to manage asthma. Astrack is a convenient, user-friendly app that monitors an individual’s asthma patterns and recommends lifestyle changes accordingly. Astrack mainly focuses on three internal factors: diet, exercise, and breathing patterns and three external factors: weather, pollen, and air quality alerts from authorized sources. By tracking these factors, Astrack recommends simple precautions that can be taken. Astrack has the potential to benefit millions of people who suffer from asthma. It would especially help parents with managing their kids’ asthma attacks by monitoring and making simple changes in their children’s daily lives.

Authors List :
Diya Kamalabharathy
Presenting Author :
Diya Kamalabharathy
Affiliations :
Poolesville High School, MD
Email :
diyakamalabharathy@gmail.com
Key Words (5 Words Maximum) :
Asthma, obesity, allergies, lifestyle, manage
]]> CAR T-CELL THERAPY AND ITS ADVANCEMENTS IN DISEASES: https://assetonline.org/car-t-cell-therapy-and-its-advancements-in-diseases/ Fri, 06 Dec 2024 08:08:30 +0000 https://assetonline.org/?p=5621 An immunotherapy that involves genetically modifying a patient’s T-cells to recognise and attack cancer cells is known as Chimeric Antigen Receptor T-Cell therapy. It is a form of groundbreaking treatment that has shown significant promise in treating blood cancers, but in some instances this therapy is also used to treat varying diseases & disorders. In addition to CAR-T, various cell therapy drugs treating cancer already exist. T-Cell therapy is currently advancing in the treatment of certain blood cancers, autoimmune diseases, neurological disorders and infectious diseases. Here I am going to cover the benefits of T-Cell therapy in diseases pertaining to and beyond the scope of oncology.

Authors List :
Adeeba Kareem
Presenting Author :
Adeeba Kareem
Affiliations :
Virginia Commonwealth University
Email :
adeebak917@gmail.com
Key Words (5 Words Maximum) :
T-cell therapy, cancer, autoimmune disorders, infectious diseases,
]]> Insight among the General Masses about the Pharmacovigilance Program of India (PvPI) https://assetonline.org/insight-among-the-general-masses-about-the-pharmacovigilance-program-of-india-pvpi/ Thu, 05 Dec 2024 02:03:26 +0000 https://assetonline.org/?p=5526 Drug therapy is an integral part of medical management. It offers health benefits but side effects and adverse drug reactions (ADRs) are some of its major disadvantages. To detect and spontaneously report ADRs and ensure the drug safety, Pharmacovigilance Program of India (PvPI) was initiated in India in 2010 under the aegis of the Indian Pharmacopoeia Commission, Ministry of Health and Family Welfare, Govt of India. Our project is one of the constituents of PvPI with an objective to determine the reporting culture and awareness of ADRs. Every year, many patients suffer from severe and even deadly adverse effects of medications, often mistaken for disease symptoms. The primary reason is the lack of knowledge and awareness among people about medications and potential ADRs. Although there have been improvements after the launch of PvPI, but much more needs to be done to facilitate spontaneous reporting and awareness about the possibility of ADRs, especially in making it accessible to the general public. This project aims to enhance public awareness and reporting of ADRs through a comprehensive study consequently the development of an accessible Android-based app for consumers.

Authors List :
Aqsa Athar, Daniyal Ali, Mohammad Rohan, Nisha, Sofia, Kulsum, Malik Hayat Hashmi, Sadia Ayub, Gufran Ali, & Syed Ziaur Rahman
Presenting Author :
Aqsa Athar and Daniyal Ali
Affiliations :
SSGE-Ibne Sina Acadamy
Email :
sa00203@gmail.com
Key Words (5 Words Maximum) :
Pharmacovigilance, Adverse drug Reaction
]]> AI for a Greener Tomorrow: Tackling Climate Change with Technology https://assetonline.org/ai-for-a-greener-tomorrow-tackling-climate-change-with-technology/ Fri, 08 Dec 2023 05:48:24 +0000 https://assetonline.org/?p=5102 This presentation delves into the transformative role of AI or Artificial Intelligence as an ally in the global endeavor to combat climate change. Against the escalating environmental challenge, the urgency to develop innovative solutions has never been more critical. The discussion unfolds across key domains where AI interventions are reshaping the landscape of climate action.
Beginning with an overview of the far-reaching consequences of climate change, the presentation will highlight the pressing need for effective strategies to reduce carbon emissions, adapt to changing environmental patterns, and foster sustainability. The narrative will progress to explore the instrumental impact of AI in climate modeling, revolutionizing accuracy, and predictive capabilities in understanding our climate and the scope of our actions on said climate.
The role of AI extends to the optimization of renewable energy sources, with a focus on enhancing efficiency in solar and wind power generation, grid management, and energy storage. The discussion then shifts to the agricultural sector, showcasing AI’s contributions to precision farming, resource optimization, and the assurance of global food security through predictive analytics. Global collaboration and data sharing take center stage as an essential component in the battle against climate change, where AI will aid us in analyzing extensive datasets to inform helpful policies. The presentation will conclude by addressing challenges, including ethical considerations, and underscores the importance of responsible AI development to ensure a sustainable and resilient future.
In summary, “AI for a Greener Tomorrow” advocates for the immense potential of AI as a transformative force in the global battle against climate change, urging continued research, innovation, and collaborative efforts to maximize its impact on creating a sustainable future for our planet all being done by a singular poster.

Authors List :
Ashar Amjad
Presenting Author :
Ashar Amjad
Affiliations :
Sharon High School, Sharon MA 02067
Email :
shaziaashraf0814@gmail.com
Key Words (5 Words Maximum) :
AI, Artificial Intelligence, Climate Change, Solar Energy, Environment
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